Web16 Jun 2024 · 转铁蛋白 (血清转铁蛋白或乳铁蛋白) 通过转铁蛋白受体 (tfrc) 介导铁摄取,fth1/ftl (铁蛋白组件) 通过自噬降解可以增加铁的水平,这些都可以促进铁死亡。而 … Web6 Apr 2024 · 转铁蛋白受体的结构及功能.doc.doc. 要】人体细胞的正常代谢需要铁,其中转铁蛋白受体(TfR)参与铁的吸收和调节。. TfR在所有细胞都呈低表达,在增殖活跃的细胞高表达。. 与正常组织相比,肿瘤组织TfR的表达显著增高,因此,TfR成为肿瘤靶向治疗的研究热 …
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Web30 May 2006 · When dietary levels of stearate (C18:0) are high, TFRC stearoylation inhibits activation of the JNK pathway and thus degradation of the mitofusin MFN2 (PubMed:26214738). By similarity. 3 publications (Microbial infection) Acts as a receptor for new-world arenaviruses: Guanarito, Junin and Machupo virus. 2 publications. Web5 Aug 2024 · 3.4 TFRC突变引起的先天性免疫缺陷 TfR1是哺乳动物发育必不可少的,Tfrc敲除小鼠显示胎死。然而,近期,发现了两个含有TFRC错义突变(Y20H)的家族。 然而, … merino gaiter smartwool striped
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Web6 Sep 2024 · The TFRC gene encodes the transferrin receptor, which is important for cellular iron uptake. Circulating apotransferrin (TF; 190000) binds 2 Fe (3+) ions to form holotransferrin, which binds to TFRC. The TFRC-holotransferrin complex is internalized by receptor-mediated endocytosis (summary by Jabara et al., 2016 ). Transferrin receptor protein 1 (TfR1), also known as Cluster of Differentiation 71 (CD71), is a protein that in humans is encoded by the TFRC gene. TfR1 is required for iron import from transferrin into cells by endocytosis. Web24 Jan 2024 · Transferrin receptor 1 (Tfr1) mediates uptake of circulating transferrin-bound iron to developing erythroid cells and other cell types. Its critical physiological function is highlighted by the embryonic lethal phenotype of Tfr1-knockout (Tfrc −/−) mice and the pathologies of several tissue-specific knockouts.We generated Tfrc Alb-Cre mice bearing … merino giant yarn where can i buy it